Cryoglobulinemia Type I in Patient with History of Monoclonal Gammopathy of Unknown Significance: A Case Report

Cryoglobulinemia is a form of vasculitis causing inflammation the blood vessels due to aggregated proteins that clump together at cold temperatures, damage skin, muscles, nerves, and other organs. An elderly black female presented with superficial ulceration overlying eschar within areas retiform purpura her bilateral thighs present for 8 months. She was previously diagnosed vaso-occlusive disease before presenting our clinic further evaluation management. Upon investigation, we have concluded patient has cryoglobulinemia type I.